human GSTA2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GSTA2.
shADV-230687
Ad-h-GSTA2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GSTA2 (glutathione S-transferase alpha 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GST2; GSTA2-2; GTA2; GTH2
Description (Vector)
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Gene ID
2939
Gene Name (Vector)
glutathione S-transferase alpha 2
Gene Symbol
GSTA2
HGNC ID
HGNC:4627
ORF Size (aa)
669
ORF Size (bp)
669 bp
RefSeq ID
NM_000846
RefSeq Synonyms
NM_000846, BC002895,
Species
human
UniGene ID
Hs.94107
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.