human OSTM1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OSTM1.
shADV-230014
Ad-h-OSTM1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OSTM1 (osteopetrosis associated transmembrane protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GIPN; GL; HSPC019; OPTB5
Description (Vector)
OSTM1 encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
Gene ID
28962
Gene Name (Vector)
osteopetrosis associated transmembrane protein 1
Gene Symbol
OSTM1
HGNC ID
HGNC:21652
ORF Size (aa)
1005
ORF Size (bp)
1005 bp
RefSeq ID
NM_014028
RefSeq Synonyms
NM_014028, BC068581,
Species
human
UniGene ID
Hs.719130
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.