human BACH2 shRNA silencing Adenovirus

Name 
Ad-h-BACH2-shRNA
Cat No 
shADV-229367
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human BACH2.

shADV-229367
Ad-h-BACH2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human BACH2 (BTB domain and CNC homolog 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BTB and CNC homolog 2; BTB and CNC homology 1, basic leucine zipper transcription factor 2; BTBD25; transcription regulator protein BACH2
Description (eCommerce)
BTB and CNC homolog 2 (BACH2) is a transcriptional regulator that acts as repressor or activator. BACH2 binds to Maf recognition elements (MARE). It induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BYV9].
Gene ID
60468
Gene Name (eCommerce)
BTB domain and CNC homolog 2
Gene Name (Vector)
BTB domain and CNC homolog 2
Gene Symbol
BACH2
HGNC ID
HGNC:14078
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2526
ORF Size (bp)
2526 bp
Protein Name (eCommerce)
Transcription regulator protein BACH2
RefSeq ID
NM_021813
RefSeq Synonyms
NM_021813, NM_001170794, BC166613,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
BTB and CNC homolog 2 (BACH2) is a transcriptional regulator that acts as repressor or activator. BACH2 binds to Maf recognition elements (MARE). It induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BYV9].
UniGene ID
Hs.269764
UniProt ID (eCommerce)
Q9BYV9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.