human TRMT1L shRNA silencing Adenovirus

Name 
Ad-h-TRMT1L-shRNA
Cat No 
shADV-229120
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRMT1L.

shADV-229120
Ad-h-TRMT1L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRMT1L (tRNA methyltransferase 1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bG120K12.3; C1orf25; MST070; MSTP070; TRM1 tRNA methyltransferase 1-like; TRM1L; TRM1-like protein; TRMT1-like protein; tRNA methyltransferase 1 homolog-like
Description (eCommerce)
The TRMT1L gene encodes for the TRMT1-like protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions [taken from NCBI Entrez Gene (Gene ID: 81627)].
Description (Vector)
TRMT1L encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene.
Gene ID
81627
Gene Name (eCommerce)
tRNA methyltransferase 1 like
Gene Name (Vector)
tRNA methyltransferase 1 like
Gene Symbol
TRMT1L
HGNC ID
HGNC:16782
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2202
ORF Size (bp)
2202 bp
Protein Name (eCommerce)
TRMT1-like protein
RefSeq ID
NM_030934
RefSeq Synonyms
NM_030934, NM_001202423, BC045535,
Research Areas
Methyltransferase,Neurobiology,RNA Binding,RNA Processing,tRNA Binding,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology,genetics,transcription_translation
Species
human
Target Sentence
The TRMT1L gene encodes for the TRMT1-like protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions [taken from NCBI Entrez Gene (Gene ID: 81627)].
UniGene ID
Hs.107149
UniProt ID (eCommerce)
Q7Z2T5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.