human ZNF444 shRNA silencing Adenovirus

Name 
Ad-h-ZNF444-shRNA
Cat No 
shADV-228576
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ZNF444.

shADV-228576
Ad-h-ZNF444-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZNF444 (zinc finger protein 444). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
endothelial zinc finger protein 2; EZF2; EZF-2; zinc finger and SCAN domain-containing protein 17; zinc finger protein 444; ZSCAN17
Description (eCommerce)
Zinc-finger protein 444 (ZNF444) belongs to the krueppel C2H2-type zinc-finger protein family and contains four C2H2-type zinc-fingers and one SCAN box domain. ZFN444 is also known as EZF-2 (endothelial zinc finger protein-2) and has been shown to bind the SREC (scavenger receptor expressed by endothelial cell) promoter.
Description (Vector)
ZNF444 encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). ZNF444 is located in a cluster of zinc finger genes on chromosome 19 at q13.4. A pseudogene of this gene is located on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
55311
Gene Name (eCommerce)
zinc finger protein 444
Gene Name (Vector)
zinc finger protein 444
Gene Symbol
ZNF444
HGNC ID
HGNC:16052
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
981
Protein Name (eCommerce)
Zinc finger protein 444
RefSeq ID
NM_018337
RefSeq Synonyms
NM_018337, NM_001253792, BC021282,
Research Areas
Host-Virus Interactions,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
Zinc-finger protein 444 (ZNF444) belongs to the krueppel C2H2-type zinc-finger protein family and contains four C2H2-type zinc-fingers and one SCAN box domain. ZFN444 is also known as EZF-2 (endothelial zinc finger protein-2) and has been shown to bind the SREC (scavenger receptor expressed by endothelial cell) promoter.
UniGene ID
Hs.24545
UniProt ID (eCommerce)
Q8N0Y2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.