human ZNF335 shRNA silencing Adenovirus

Name 
Ad-h-ZNF335-shRNA
Cat No 
shADV-228493
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ZNF335.

shADV-228493
Ad-h-ZNF335-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZNF335 (zinc finger protein 335). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MCPH10; NIF1; NIF-1; NIF2; NRC-interacting factor 1; zinc finger protein 335; zinc-finger/leucine-zipper co-transducer NIF1
Description (eCommerce)
NRC-Interacting Factor 1 (NIF1) interacts with the nuclear receptor transcriptional coactivator NRC and enhances ligand-dependent transcriptional activation by nuclear hormone receptors as well as c-Fos and c-Jun. NIF1 may function to influence chromatin structure.
Description (Vector)
ZNF335 enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure.
Gene ID
63925
Gene Name (eCommerce)
zinc finger protein 335
Gene Name (Vector)
zinc finger protein 335
Gene Symbol
ZNF335
HGNC ID
HGNC:15807
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4029
ORF Size (bp)
4029 bp
Protein Name (eCommerce)
Zinc finger protein 335
RefSeq ID
NM_022095
RefSeq Synonyms
NM_022095, BC166679,
Research Areas
Epigenetic Regulation of Gene Expression,Neurobiology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
neurobiology,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
NRC-Interacting Factor 1 (NIF1) interacts with the nuclear receptor transcriptional coactivator NRC and enhances ligand-dependent transcriptional activation by nuclear hormone receptors as well as c-Fos and c-Jun. NIF1 may function to influence chromatin structure.
UniGene ID
Hs.174193
UniProt ID (eCommerce)
Q9H4Z2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.