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human ZMYM3 shRNA silencing Adenovirus

Name 
Ad-h-ZMYM3-shRNA
Cat No 
shADV-228285
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ZMYM3.

shADV-228285
Ad-h-ZMYM3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZMYM3 (zinc finger MYM-type containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DXS6673E; MYM; XFIM; zinc finger MYM-type protein 3; zinc finger protein 261; zinc finger, MYM-type 3; ZNF198L2; ZNF261
Description (eCommerce)
Zinc-finger protein 261(ZNF261) is a candidate gene for X-linked mental retardation. ZNF261 is a component of a multi-protein HDAC1,2 complex and associates with BHC110. ZNF261 may be a DNA binding subunit for the histone deacetylase and transcriptional repressing activity of the HDAC1,2/BHC110 complex.
Description (Vector)
ZMYM3 is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene.
Gene ID
9203
Gene Name (eCommerce)
zinc finger MYM-type containing 3
Gene Name (Vector)
zinc finger MYM-type containing 3
Gene Symbol
ZMYM3
HGNC ID
HGNC:13054
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4113
ORF Size (bp)
4113 bp
Protein Name (eCommerce)
Zinc finger MYM-type protein 3
RefSeq ID
NM_005096
RefSeq Synonyms
NM_201599, NM_005096, NM_001171163, NM_001171162, BC069057,
Research Areas
Cytoskeleton,Histone Modification,Neurobiology,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Zinc-finger protein 261(ZNF261) is a candidate gene for X-linked mental retardation. ZNF261 is a component of a multi-protein HDAC1,2 complex and associates with BHC110. ZNF261 may be a DNA binding subunit for the histone deacetylase and transcriptional repressing activity of the HDAC1,2/BHC110 complex.
UniGene ID
Hs.522684
UniProt ID (eCommerce)
Q14202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.