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human ZMIZ1 shRNA silencing Adenovirus

Name 
Ad-h-ZMIZ1-shRNA
Cat No 
shADV-228281
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ZMIZ1.

shADV-228281
Ad-h-ZMIZ1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZMIZ1 (zinc finger MIZ-type containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10
Description (Vector)
ZMIZ1 encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia.
Gene ID
57178
Gene Name (Vector)
zinc finger MIZ-type containing 1
Gene Symbol
ZMIZ1
HGNC ID
HGNC:16493
ORF Size (aa)
3204
ORF Size (bp)
3204 bp
RefSeq ID
NM_020338
RefSeq Synonyms
NM_020338, BC172361,
Species
human
UniGene ID
Hs.193118

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.