human ZFYVE16 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ZFYVE16.
shADV-228235
Ad-h-ZFYVE16-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ZFYVE16 (zinc finger FYVE-type containing 16). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Endofin; Endosome-associated FYVE domain protein; endosome-associated FYVE-domain protein; PPP1R69; protein phosphatase 1, regulatory subunit 69; zinc finger FYVE domain-containing protein 16; zinc finger, FYVE domain containing 16
Description (eCommerce)
Endofin may be involved in regulating membrane trafficking in the endosomal pathway. Overexpression of Endofin induces endosome aggregation. It is required to target TOM1 to endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z3T8].
Description (Vector)
The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule (Seet et al., 2004 (PubMed 14613930)).(supplied by OMIM, Mar 2008)
Gene ID
9765
Gene Name (eCommerce)
zinc finger FYVE-type containing 16
Gene Name (Vector)
zinc finger FYVE-type containing 16
Gene Symbol
ZFYVE16
HGNC ID
HGNC:20756
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2430
ORF Size (bp)
2430 bp
Protein Name (eCommerce)
Zinc finger FYVE domain-containing protein 16
RefSeq ID
NM_014733
RefSeq Synonyms
NM_014733, NM_001284237, NM_001284236, NM_001105251, BC030808,
Research Areas
EGFR Signaling,Kinase/Phosphatase,Lysosomal Transport,Signal Transduction,TGF-beta Signaling,Transport,Zinc-finger
Research Areas (Faceted)
signal_transduction,cell_biology,immunology,cell_biology
Species
human
Target Sentence
Endofin may be involved in regulating membrane trafficking in the endosomal pathway. Overexpression of Endofin induces endosome aggregation. It is required to target TOM1 to endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z3T8].
UniGene ID
Hs.660410
UniProt ID (eCommerce)
Q7Z3T8
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.