human ZCRB1 shRNA silencing Adenovirus

Name 
Ad-h-ZCRB1-shRNA
Cat No 
shADV-228135
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ZCRB1.

shADV-228135
Ad-h-ZCRB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MADP1; MADP-1; RBM36; SNRNP31; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; ZCCHC19; zinc finger CCHC-type and RNA binding motif 1; zinc finger CCHC-type and RNA-binding motif-containing protein 1
Description (eCommerce)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) is a component of the U11/U12 snRNPs that are part of the U12-type spliceosome  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TBF4].
Description (Vector)
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
Gene ID
85437
Gene Name (eCommerce)
zinc finger CCHC-type and RNA binding motif containing 1
Gene Name (Vector)
zinc finger CCHC-type and RNA binding motif containing 1
Gene Symbol
ZCRB1
HGNC ID
HGNC:29620
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
654
Protein Name (eCommerce)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
RefSeq ID
NM_033114
RefSeq Synonyms
NM_033114, BC022543,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) is a component of the U11/U12 snRNPs that are part of the U12-type spliceosome  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TBF4].
UniGene ID
Hs.496279
UniProt ID (eCommerce)
Q8TBF4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.