human WFDC3 shRNA silencing Adenovirus

Name
Ad-h-WFDC3-shRNA

Cat No
shADV-227767

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human WFDC3.

shADV-227767

Ad-h-WFDC3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WFDC3 (WAP four-disulfide core domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

dJ447F3.3; WAP14

Description (Vector)

WFDC3 encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. WFDC3 belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined.

Gene ID

140686

Gene Name (Vector)

WAP four-disulfide core domain 3

Gene Symbol

WFDC3

HGNC ID

HGNC:15957

ORF Size (aa)

696

RefSeq ID

NM_080614

RefSeq Synonyms

NM_080614, BC148860, BC146426,

Species

human

UniGene ID

Hs.419126

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.