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human WDR20 shRNA silencing Adenovirus

Name 
Ad-h-WDR20-shRNA
Cat No 
shADV-227648
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human WDR20.

shADV-227648
Ad-h-WDR20-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WDR20 (WD repeat domain 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DMR; Protein DMR; WD repeat-containing protein 20
Description (eCommerce)
WDR20 (WD repeat-containing protein 20) contains five WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR20 has not been characterized.
Description (Vector)
WDR20 encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
91833
Gene Name (eCommerce)
WD repeat domain 20
Gene Name (Vector)
WD repeat domain 20
Gene Symbol
WDR20
HGNC ID
HGNC:19667
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1710
ORF Size (bp)
1710 bp
Protein Name (eCommerce)
WD repeat-containing protein 20
RefSeq ID
NM_144574
RefSeq Synonyms
NM_181308, NM_181291, NM_144574, NM_001330228, NM_001320130, NM_001242418, NM_001242417, NM_001242416, NM_001242415, NM_001242414, BC028387,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
WDR20 (WD repeat-containing protein 20) contains five WD repeats and is a member of the WD family of proteins. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR20 has not been characterized.
UniGene ID
Hs.36859
UniProt ID (eCommerce)
Q8TBZ3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.