human WDR1 shRNA silencing Adenovirus

Name
Ad-h-WDR1-shRNA

Cat No
shADV-227639

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human WDR1.

shADV-227639

Ad-h-WDR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WDR1 (WD repeat domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

actin-interacting protein 1; AIP1; epididymis secretory protein Li 52; HEL-S-52; NORI-1; WD repeat-containing protein 1

Description (eCommerce)

WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. WDR1 may help induce the disassembly of actin filaments [taken from NCBI Entrez Gene (Gene ID: 9948)].

Description (Vector)

WDR1 encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

9948

Gene Name (eCommerce)

WD repeat domain 1

Gene Name (Vector)

WD repeat domain 1

Gene Symbol

WDR1

HGNC ID

HGNC:12754

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1821

ORF Size (bp)

1821 bp

Protein Name (eCommerce)

WD repeat-containing protein 1

RefSeq ID

NM_005112

RefSeq Synonyms

NM_017491, NM_005112, BC030541, BC002489, BC000201,

Research Areas

Cytoskeleton,Immunology,Neurobiology,T-cell Receptor Signaling

Research Areas (Faceted)

signal_transduction,cell_biology,immunology,neurobiology,signal_transduction

Species

human

Target Sentence

WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. WDR1 may help induce the disassembly of actin filaments [taken from NCBI Entrez Gene (Gene ID: 9948)].

UniGene ID

Hs.713658

UniProt ID (eCommerce)

O75083

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.