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human WBP4 shRNA silencing Adenovirus

Name 
Ad-h-WBP4-shRNA
Cat No 
shADV-227613
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human WBP4.

shADV-227613
Ad-h-WBP4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human WBP4 (WW domain binding protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
domain-containing binding protein 4; FBP21; formin binding protein 21; Formin-binding protein 21; WBP-4; WW domain-binding protein 4; WW domain-containing binding protein 4; WW domain-containing-binding protein 4
Description (eCommerce)
The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. WW domain-binding protein 4 (WBP4) is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A [taken from NCBI Entrez Gene (Gene ID: 11193)].
Description (Vector)
WBP4 encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A.
Gene ID
11193
Gene Name (eCommerce)
WW domain binding protein 4
Gene Name (Vector)
WW domain binding protein 4
Gene Symbol
WBP4
HGNC ID
HGNC:12739
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1131
Protein Name (eCommerce)
WW domain-binding protein 4
RefSeq ID
NM_007187
RefSeq Synonyms
NM_007187, BC108310, BC104879,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. WW domain-binding protein 4 (WBP4) is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A [taken from NCBI Entrez Gene (Gene ID: 11193)].
UniGene ID
Hs.411300
UniProt ID (eCommerce)
O75554

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.