human VSNL1 shRNA silencing Adenovirus

Name
Ad-h-VSNL1-shRNA

Cat No
shADV-227563

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human VSNL1.

shADV-227563

Ad-h-VSNL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VSNL1 (visinin like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1

Description (Vector)

VSNL1 is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Gene ID

7447

Gene Name (Vector)

visinin like 1

Gene Symbol

VSNL1

HGNC ID

HGNC:12722

ORF Size (aa)

576

RefSeq ID

NM_003385

RefSeq Synonyms

NM_003385, BC022012,

Species

human

UniGene ID

Hs.444212

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.