human VEGFB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human VEGFB.
shADV-227458
Ad-h-VEGFB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human VEGFB (vascular endothelial growth factor B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
VEGFL; VRF
Description (Vector)
VEGFB encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Gene ID
7423
Gene Name (Vector)
vascular endothelial growth factor B
Gene Symbol
VEGFB
HGNC ID
HGNC:12681
ORF Size (aa)
624
RefSeq ID
NM_003377
RefSeq Synonyms
NM_003377, NM_001243733, BC008818,
Species
human
UniGene ID
Hs.78781
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.