human VAPA shRNA silencing Adenovirus

Name 
Ad-h-VAPA-shRNA
Cat No 
shADV-227393
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human VAPA.

shADV-227393
Ad-h-VAPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VAPA (VAMP associated protein A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
33 kDa VAMP-associated protein; epididymis secretory sperm binding protein; hVAP-33; VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; VAMP-A; VAMP-associated protein A; VAP33; VAP-33; VAP-A; vesicle-associated membrane protein-associated protein A
Description (eCommerce)
VAP-33 is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. VAP-33 may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility [taken from NCBI Entrez Gene (Gene ID: 9218)].
Description (Vector)
VAPA is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Gene ID
9218
Gene Name (eCommerce)
VAMP associated protein A
Gene Name (Vector)
VAMP associated protein A
Gene Symbol
VAPA
HGNC ID
HGNC:12648
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
750
Protein Name (eCommerce)
Vesicle-associated membrane protein-associated protein A
RefSeq ID
NM_003574
RefSeq Synonyms
NM_194434, NM_003574, BC002992,
Research Areas
Apoptosis,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,NF-kB Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
VAP-33 is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. VAP-33 may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility [taken from NCBI Entrez Gene (Gene ID: 9218)].
UniGene ID
Hs.699980
UniProt ID (eCommerce)
Q9P0L0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.