human USP13 shRNA silencing Adenovirus

Name 
Ad-h-USP13-shRNA
Cat No 
shADV-227285
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human USP13.

shADV-227285
Ad-h-USP13-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human USP13 (ubiquitin specific peptidase 13 (isopeptidase T-3)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. USP13 (ubiquitin specific peptidase 13) is a member of this family.
Gene ID
8975
Gene Name (eCommerce)
ubiquitin specific peptidase 13
Gene Name (Vector)
ubiquitin specific peptidase 13 (isopeptidase T-3)
Gene Symbol
USP13
HGNC ID
HGNC:12611
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2592
ORF Size (bp)
2592 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 13
RefSeq ID
NM_003940
RefSeq Synonyms
NM_003940, BC016146,
Research Areas
Autophagy,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. USP13 (ubiquitin specific peptidase 13) is a member of this family.
UniGene ID
Hs.175322
UniProt ID (eCommerce)
Q92995

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.