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human UROS shRNA silencing Adenovirus

Name 
Ad-h-UROS-shRNA
Cat No 
shADV-227266
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human UROS.

shADV-227266
Ad-h-UROS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UROS (uroporphyrinogen III synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
UROIIIS
Description (Vector)
UROS catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease).
Gene ID
7390
Gene Name (Vector)
uroporphyrinogen III synthase
Gene Symbol
UROS
HGNC ID
HGNC:12592
ORF Size (aa)
798
RefSeq ID
NM_000375
RefSeq Synonyms
NM_001324039, NM_001324038, NM_001324037, NM_001324036, NM_000375, BC002573,
Species
human
UniGene ID
Hs.501376

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.