human UPP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human UPP1.
shADV-227236
Ad-h-UPP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human UPP1 (uridine phosphorylase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
UDRPASE; UP; UPASE; UPP
Description (Vector)
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate. Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be incorporated into RNA or DNA (Watanabe and Uchida, 1995 (PubMed 7488099)).(supplied by OMIM, Aug 2009)
Gene ID
7378
Gene Name (Vector)
uridine phosphorylase 1
Gene Symbol
UPP1
HGNC ID
HGNC:12576
ORF Size (aa)
522
RefSeq ID
NM_003364
RefSeq Synonyms
NM_181597, NM_003364, NM_001287430, NM_001287429, NM_001287428, NM_001287426, BC047030, BC007348, BC001405,
Species
human
UniGene ID
Hs.488240
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.