human UBR7 shRNA silencing Adenovirus

Name 
Ad-h-UBR7-shRNA
Cat No 
shADV-227083
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human UBR7.

shADV-227083
Ad-h-UBR7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C14orf130; N-recognin-7; putative E3 ubiquitin-protein ligase UBR7; RING-type E3 ubiquitin transferase UBR7
Description (eCommerce)
Putative E3 ubiquitin-protein ligase UBR7 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. UBR7 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N806].
Gene ID
55148
Gene Name (eCommerce)
ubiquitin protein ligase E3 component n-recognin 7 (putative)
Gene Name (Vector)
ubiquitin protein ligase E3 component n-recognin 7 (putative)
Gene Symbol
UBR7
HGNC ID
HGNC:20344
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
Protein Name (eCommerce)
Putative E3 ubiquitin-protein ligase UBR7
RefSeq ID
NM_175748
RefSeq Synonyms
NM_175748, BC051819, BC017013, BC015046,
Research Areas
Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Putative E3 ubiquitin-protein ligase UBR7 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. UBR7 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8N806].
UniGene ID
Hs.648806
UniProt ID (eCommerce)
Q8N806

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.