human TSGA14 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CEP41.
shADV-226603
Ad-h-TSGA14-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CEP41 (centrosomal protein 41). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
centrosomal protein 41 kDa; centrosomal protein 41kDa; centrosomal protein of 41 kDa; Cep41; JBTS15; testis specific protein A14; testis specific, 14; testis-specific gene A14 protein; TSGA14
Description (eCommerce)
CEP41 (centrosomal protein of 41 kDa) is the protein product of the testis-specific gene A14 (TSGA14). TSGA14 was originally identified as a gene adjacent to the imprinted gene MEST. Studies of TSGA14 revealed that unlike MEST, TSGA14 is not an imprinted gene. CEP41 was also identified as a true centrosomal protein in a mass-spectometry-based proteomic analysis of human centrosomes. The role of CEP41 in the centrosome remains uncharacterized.
Description (Vector)
CEP41 encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants.
Gene ID
95681
Gene Name (eCommerce)
centrosomal protein 41
Gene Name (Vector)
centrosomal protein 41
Gene Symbol
CEP41
HGNC ID
HGNC:12370
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
906
ORF Size (bp)
906 bp
Protein Name (eCommerce)
Centrosomal protein of 41 kDa
RefSeq ID
NM_018718
RefSeq Synonyms
NM_018718, NM_001257160, NM_001257159, NM_001257158, BC056162,
Research Areas
Cell Cycle,Cytoskeleton,Neurobiology
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,neurobiology
Species
human
Target Sentence
CEP41 (centrosomal protein of 41 kDa) is the protein product of the testis-specific gene A14 (TSGA14). TSGA14 was originally identified as a gene adjacent to the imprinted gene MEST. Studies of TSGA14 revealed that unlike MEST, TSGA14 is not an imprinted gene. CEP41 was also identified as a true centrosomal protein in a mass-spectometry-based proteomic analysis of human centrosomes. The role of CEP41 in the centrosome remains uncharacterized.
UniGene ID
Hs.368315
UniProt ID (eCommerce)
Q9BYV8
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.