human TRPM5 shRNA silencing Adenovirus

Name 
Ad-h-TRPM5-shRNA
Cat No 
shADV-226555
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRPM5.

shADV-226555
Ad-h-TRPM5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRPM5 (transient receptor potential cation channel subfamily M member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LTRPC5; MTR1
Description (Vector)
TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. TRPM5 is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
Gene ID
29850
Gene Name (Vector)
transient receptor potential cation channel subfamily M member 5
Gene Symbol
TRPM5
HGNC ID
HGNC:14323
ORF Size (aa)
3498
ORF Size (bp)
3498 bp
RefSeq ID
NM_014555
RefSeq Synonyms
NM_014555, BC143353, BC143351, BC093789, BC093787,
Species
human
UniGene ID
Hs.272287

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.