human TRIP10 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TRIP10.
shADV-226495
Ad-h-TRIP10-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TRIP10 (thyroid hormone receptor interactor 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cdc42-interacting protein 4; CIP4; HSTP; protein Felic; salt tolerant protein; salt tolerator; STOT; STP; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Description (eCommerce)
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
Gene ID
9322
Gene Name (eCommerce)
thyroid hormone receptor interactor 10
Gene Name (Vector)
thyroid hormone receptor interactor 10
Gene Symbol
TRIP10
HGNC ID
HGNC:12304
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
Protein Name (eCommerce)
Cdc42-interacting protein 4
RefSeq ID
NM_004240
RefSeq Synonyms
NM_004240, NM_001288963, NM_001288962, BC013002,
Research Areas
Cytoskeleton,Golgi Apparatus,Insulin Signaling,Lysosome,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
UniGene ID
Hs.515094
UniProt ID (eCommerce)
Q15642
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.