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human TRIM22 shRNA silencing Adenovirus

Name 
Ad-h-TRIM22-shRNA
Cat No 
shADV-226411
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRIM22.

shADV-226411
Ad-h-TRIM22-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRIM22 (tripartite motif containing 22). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GPSTAF50; RNF94; STAF50
Description (Vector)
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants.
Gene ID
10346
Gene Name (Vector)
tripartite motif containing 22
Gene Symbol
TRIM22
HGNC ID
HGNC:16379
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_006074
RefSeq Synonyms
NM_006074, NM_001199573, BC035582, BC022281,
Species
human
UniGene ID
Hs.684559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.