human TOR1AIP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TOR1AIP1.
shADV-226213
Ad-h-TOR1AIP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TOR1AIP1 (torsin 1A interacting protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
lamina-associated polypeptide 1B; lamin-associated protein 1B; LAP1; LAP1B; LGMD2Y; torsin A interacting protein 1; torsin-1A-interacting protein 1
Description (eCommerce)
Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.
Description (Vector)
TOR1AIP1 encodes a type 2 integral membrane protein that binds A- and B-type laminins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants.
Gene ID
26092
Gene Name (eCommerce)
torsin 1A interacting protein 1
Gene Name (Vector)
torsin 1A interacting protein 1
Gene Symbol
TOR1AIP1
HGNC ID
HGNC:29456
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
Protein Name (eCommerce)
Torsin-1A-interacting protein 1
RefSeq ID
NM_015602
RefSeq Synonyms
NM_015602, NM_001267578, BC023247,
Research Areas
Cell Biology,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Lamina-associated polypeptide 1B (LAPB1) binds to A- and B-type lamins. It is a single-pass membrane protein that localizes to the inner membrane of the nucleus and may play a role in membrane attachment and the assembly of the nuclear lamina. LAPB1 is also called torsin-1A-interacting protein 1 (TOR1AIP1) due to its association with torsin, an ATPase of the AAA- (adenosine triphosphatases associated with diverse cellular activities) family of proteins.
UniGene ID
Hs.496459
UniProt ID (eCommerce)
Q5JTV8
Recently Viewed Products
Ad-h-SERPINA12
Cat No: ADV-222671
AAV-h-DOLPP1-shRNA
Cat No: shAAV-207254
AAV-r-CLDN18-shRNA
Cat No: shAAV-293002
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.