human THOC1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human THOC1.
shADV-225448
Ad-h-THOC1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human THOC1 (THO complex 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HPR1; hTREX84; nuclear matrix protein p84; P84; P84N5; THO complex subunit 1; tho1
Description (eCommerce)
THO complex subunit 1 (THOC1) is a component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and UAP56, THO forms a complex with the transcription/export (TREX) complex. The TREX complex specifically associates with spliced mRNA and functions in mRNA export.
Description (Vector)
HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).(supplied by OMIM, Nov 2010)
Gene ID
9984
Gene Name (eCommerce)
THO complex 1
Gene Name (Vector)
THO complex 1
Gene Symbol
THOC1
HGNC ID
HGNC:19070
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1974
ORF Size (bp)
1974 bp
Protein Name (eCommerce)
THO complex subunit 1
RefSeq ID
NM_005131
RefSeq Synonyms
NM_005131, BC010381,
Research Areas
Apoptosis,Gene Expression,Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport,Signal Transduction,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,genetics,transcription_translation,infectious_disease,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
THO complex subunit 1 (THOC1) is a component of the THO complex, which is composed of THOC1, THOC2, THOC5, THOC6 and THOC7. Together with THOC3, THOC4 and UAP56, THO forms a complex with the transcription/export (TREX) complex. The TREX complex specifically associates with spliced mRNA and functions in mRNA export.
UniGene ID
Hs.712543
UniProt ID (eCommerce)
Q96FV9
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.