human TGFBR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TGFBR1.
shADV-225390
Ad-h-TGFBR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TGFBR1 (transforming growth factor beta receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; tbetaR-I; TGFR-1
Description (Vector)
TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
7046
Gene Name (Vector)
transforming growth factor beta receptor 1
Gene Symbol
TGFBR1
HGNC ID
HGNC:11772
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_004612
RefSeq Synonyms
NM_004612, NM_001306210, NM_001130916, BC071181,
Species
human
UniGene ID
Hs.494622
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.