human TGFBI shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TGFBI.
shADV-225388
Ad-h-TGFBI-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TGFBI (transforming growth factor beta induced). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1
Description (Vector)
TGFBI encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Gene ID
7045
Gene Name (Vector)
transforming growth factor beta induced
Gene Symbol
TGFBI
HGNC ID
HGNC:11771
ORF Size (aa)
2052
ORF Size (bp)
2052 bp
RefSeq ID
NM_000358
RefSeq Synonyms
NM_000358, BC004972, BC000097,
Species
human
UniGene ID
Hs.369397
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.