human TCN2 shRNA silencing Adenovirus

Name
Ad-h-TCN2-shRNA

Cat No
shADV-225235

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TCN2.

shADV-225235

Ad-h-TCN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TCN2 (transcobalamin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

D22S676; D22S750; II; TC; TC II; TC-2; TC2; TCII

Description (Vector)

TCN2 encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

Gene ID

6948

Gene Name (Vector)

transcobalamin 2

Gene Symbol

TCN2

HGNC ID

HGNC:11653

ORF Size (aa)

1284

ORF Size (bp)

1284 bp

RefSeq ID

NM_000355

RefSeq Synonyms

NM_001184726, NM_000355, BC011239, BC001176,

Species

human

UniGene ID

Hs.417948

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.