human TCAP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TCAP.
shADV-225173
Ad-h-TCAP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TCAP (titin-cap). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1N; CMH25; LGMD2G; T-cap; TELE; telethonin
Description (Vector)
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
Gene ID
8557
Gene Name (Vector)
titin-cap
Gene Symbol
TCAP
HGNC ID
HGNC:11610
ORF Size (aa)
504
RefSeq ID
NM_003673
RefSeq Synonyms
NM_003673, BC013330, BC012628,
Species
human
UniGene ID
Hs.514146
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.