human TBL3 shRNA silencing Adenovirus

Name 
Ad-h-TBL3-shRNA
Cat No 
shADV-225135
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TBL3.

shADV-225135
Ad-h-TBL3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBL3 (transducin beta like 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SAZD; transducin beta-like protein 3; UTP13; WD repeat-containing protein SAZD; WD-repeat protein SAZD
Description (eCommerce)
Transducin beta-like protein 3 (TBL3) has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiatio [taken from NCBI Entrez Gene (Gene ID: 10607)].
Description (Vector)
TBL3 has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet.
Gene ID
10607
Gene Name (eCommerce)
transducin beta like 3
Gene Name (Vector)
transducin beta like 3
Gene Symbol
TBL3
HGNC ID
HGNC:11587
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2427
ORF Size (bp)
2427 bp
Protein Name (eCommerce)
Transducin beta-like protein 3
RefSeq ID
NM_006453
RefSeq Synonyms
NM_006453, BC035409, BC014007, BC010231,
Research Areas
RNA Processing,Signal Transduction
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Transducin beta-like protein 3 (TBL3) has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiatio [taken from NCBI Entrez Gene (Gene ID: 10607)].
UniGene ID
Hs.513267
UniProt ID (eCommerce)
Q12788

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.