human TBCB shRNA silencing Adenovirus

Name 
Ad-h-TBCB-shRNA
Cat No 
shADV-225114
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TBCB.

shADV-225114
Ad-h-TBCB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBCB (tubulin folding cofactor B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CG22; CKAP1; CKAPI; cytoskeleton associated protein 1; Cytoskeleton-associated protein 1; cytoskeleton-associated protein CKAPI; tubulin-folding cofactor B; tubulin-specific chaperone B
Description (eCommerce)
Tubulin-folding cofactor B (TBCB) binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99426].
Gene ID
1155
Gene Name (eCommerce)
tubulin folding cofactor B
Gene Name (Vector)
tubulin folding cofactor B
Gene Symbol
TBCB
HGNC ID
HGNC:1989
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
735
ORF Size (bp)
735 bp
Protein Name (eCommerce)
Tubulin-folding cofactor B
RefSeq ID
NM_001281
RefSeq Synonyms
NM_001300971, NM_001281, BC052812, BC005969,
Research Areas
Cytoskeleton,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,Neurogenesis,Protein Folding,Translational Control
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,neurobiology,transcription_translation
Species
human
Target Sentence
Tubulin-folding cofactor B (TBCB) binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99426].
UniGene ID
Hs.31053
UniProt ID (eCommerce)
Q99426

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.