human TBC1D1 shRNA silencing Adenovirus

Name
Ad-h-TBC1D1-shRNA

Cat No
shADV-225053

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TBC1D1.

shADV-225053

Ad-h-TBC1D1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TBC1D1 (TBC1 domain family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

TBC; TBC1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1

Description (eCommerce)

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]) [taken from NCBI Entrez Gene (Gene ID: 23216)].

Description (Vector)

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 (PubMed 10965142)).(supplied by OMIM, Mar 2008)

Gene ID

23216

Gene Name (eCommerce)

TBC1 domain family member 1

Gene Name (Vector)

TBC1 domain family member 1

Gene Symbol

TBC1D1

HGNC ID

HGNC:11578

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3507

ORF Size (bp)

3507 bp

Protein Name (eCommerce)

TBC1 domain family member 1

RefSeq ID

NM_015173

RefSeq Synonyms

NM_015173, NM_001253915, NM_001253914, NM_001253913, NM_001253912, BC050321,

Research Areas

Cell Biology,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology

Species

human

Target Sentence

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]) [taken from NCBI Entrez Gene (Gene ID: 23216)].

UniGene ID

Hs.176503

UniProt ID (eCommerce)

Q86TI0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.