human TARBP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TARBP2.
shADV-224972
Ad-h-TARBP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TARBP2 (TARBP2, RISC loading complex RNA binding subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LOQS; TRBP; TRBP1; TRBP2
Description (Vector)
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
Gene ID
6895
Gene Name (Vector)
TARBP2, RISC loading complex RNA binding subunit
Gene Symbol
TARBP2
HGNC ID
HGNC:11569
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_004178
RefSeq Synonyms
NM_134324, NM_134323, NM_004178, BC005860,
Species
human
UniGene ID
Hs.326
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.