human TAL1 shRNA silencing Adenovirus

Name 
Ad-h-TAL1-shRNA
Cat No 
shADV-224950
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TAL1.

shADV-224950
Ad-h-TAL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHa17; class A basic helix-loop-helix protein 17; SCL; stem cell protein; tal-1; tal-1 product; T-cell acute lymphocytic leukemia 1; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; TCL5
Description (eCommerce)
T-cell acute lymphocytic leukemia protein 1 (TAL1) is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. TAL1 serves as a positive regulator of erythroid differentiation (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17542].
Gene ID
6886
Gene Name (eCommerce)
TAL bHLH transcription factor 1, erythroid differentiation factor
Gene Name (Vector)
TAL bHLH transcription factor 1, erythroid differentiation factor
Gene Symbol
TAL1
HGNC ID
HGNC:11556
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
ORF Size (bp)
996 bp
Protein Name (eCommerce)
T-cell acute lymphocytic leukemia protein 1
RefSeq ID
NM_003189
RefSeq Synonyms
NM_003189, NM_001290406, NM_001290405, NM_001290404, NM_001290403, NM_001287347, BC160033,
Research Areas
Angiogenesis,Cancer,Cell Cycle,Immunology,Neurobiology,Neurodevelopment,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,developmental_biology,cell_biology,cell_cycle,immunology,neurobiology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
T-cell acute lymphocytic leukemia protein 1 (TAL1) is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. TAL1 serves as a positive regulator of erythroid differentiation (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17542].
UniGene ID
Hs.709194
UniProt ID (eCommerce)
P17542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.