human TAF8 shRNA silencing Adenovirus

Name 
Ad-h-TAF8-shRNA
Cat No 
shADV-224931
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TAF8.

shADV-224931
Ad-h-TAF8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TAF8 (TATA-box binding protein associated factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hTAFII43; II; protein taube nuss; TAF; TAF(II)43; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; TAFII43; TAFII-43; TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 45/50kDa; taube nuss homolog; TBN; TBP-associated factor 43 kDa; TBP-associated factor 8; TBP-associated factor TAFII43; TBP-associated factor, RNA polymerase II, 43 kD; transcription initiation factor TFIID 43 kDa subunit; transcription initiation factor TFIID subunit 8
Description (eCommerce)
Transcription initiation factor TFIID subunit 8 is one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. TAF8 contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10 [taken from NCBI Entrez Gene (Gene ID: 129685)].
Description (Vector)
TAF8 encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene ID
129685
Gene Name (eCommerce)
TATA-box binding protein associated factor 8
Gene Name (Vector)
TATA-box binding protein associated factor 8
Gene Symbol
TAF8
HGNC ID
HGNC:17300
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
936
Protein Name (eCommerce)
Transcription initiation factor TFIID subunit 8
RefSeq ID
NM_138572
RefSeq Synonyms
NM_138572, BC119679, BC119678, BC033728,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Transcription initiation factor TFIID subunit 8 is one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. TAF8 contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10 [taken from NCBI Entrez Gene (Gene ID: 129685)].
UniGene ID
Hs.520122
UniProt ID (eCommerce)
Q7Z7C8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.