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human SYNCRIP shRNA silencing Adenovirus

Name 
Ad-h-SYNCRIP-shRNA
Cat No 
shADV-224810
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SYNCRIP.

shADV-224810
Ad-h-SYNCRIP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
glycine- and tyrosine-rich RNA-binding protein; GRYRBP; GRY-RBP; heterogeneous nuclear ribonucleoprotein Q; hnRNP Q; HNRNPQ; hnRNP-Q; HNRPQ1; NS1-associated protein 1; NSAP1; PP68; Synaptotagmin-binding, cytoplasmic RNA-interacting protein
Description (eCommerce)
This protein is a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family, which are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. [provided by RefSeq, Dec 2011] [taken from NCBI Entrez Gene (Gene ID: 10492)].
Description (Vector)
SYNCRIP encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20.
Gene ID
10492
Gene Name (eCommerce)
synaptotagmin binding cytoplasmic RNA interacting protein
Gene Name (Vector)
synaptotagmin binding cytoplasmic RNA interacting protein
Gene Symbol
SYNCRIP
HGNC ID
HGNC:16918
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1233
ORF Size (bp)
1233 bp
Protein Name (eCommerce)
Heterogeneous nuclear ribonucleoprotein Q
RefSeq ID
NM_006372
RefSeq Synonyms
NM_006372, NM_001253771, NM_001159677, NM_001159676, NM_001159675, NM_001159674, NM_001159673, BC040844, BC032643,
Research Areas
Gene Expression,Host-Virus Interactions,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,infectious_disease,transcription_translation
Species
human
Target Sentence
This protein is a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family, which are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. [provided by RefSeq, Dec 2011] [taken from NCBI Entrez Gene (Gene ID: 10492)].
UniGene ID
Hs.571177
UniProt ID (eCommerce)
O60506

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.