human SUMO4 shRNA silencing Adenovirus

Name 
Ad-h-SUMO4-shRNA
Cat No 
shADV-224746
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SUMO4.

shADV-224746
Ad-h-SUMO4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SUMO4 (small ubiquitin-like modifier 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
dJ281H8.4; IDDM5; SMT3H4; SUMO-4
Description (Vector)
SUMO4 is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
Gene ID
387082
Gene Name (Vector)
small ubiquitin-like modifier 4
Gene Symbol
SUMO4
HGNC ID
HGNC:21181
ORF Size (aa)
288
RefSeq ID
NM_001002255
RefSeq Synonyms
NM_001002255, BC130305,
Species
human
UniGene ID
Hs.657168

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.