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human SUMO1 shRNA silencing Adenovirus

Name 
Ad-h-SUMO1-shRNA
Cat No 
shADV-224732
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SUMO1.

shADV-224732
Ad-h-SUMO1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SUMO1 (small ubiquitin-like modifier 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1
Description (Vector)
SUMO1 encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Gene ID
7341
Gene Name (Vector)
small ubiquitin-like modifier 1
Gene Symbol
SUMO1
HGNC ID
HGNC:12502
ORF Size (aa)
306
RefSeq ID
NM_003352
RefSeq Synonyms
NM_003352, NM_001005782, NM_001005781, BC066306, BC053528, BC006462,
Species
human
UniGene ID
Hs.596171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.