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human STX1B shRNA silencing Adenovirus

Name 
Ad-h-STX1B-shRNA
Cat No 
shADV-224662
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human STX1B.

shADV-224662
Ad-h-STX1B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human STX1B (syntaxin 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
83
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GEFSP9; STX1B1; STX1B2
Description (Vector)
Syntaxins are cellular receptors for transport vesicles (see MIM 603765). One of these proteins, designated syntaxin 1B (STX1B), is directly implicated in the process of calcium-dependent synaptic transmission in rat brain (Smirnova et al., 1993 (PubMed 8105537)). The expression of this protein is transiently induced by long-term potentiation of synaptic responses in the rat hippocampus. The protein may play an important role in the excitatory pathway of synaptic transmission, which is known to be implicated in several neurologic diseases.(supplied by OMIM, Nov 2010)
Gene ID
112755
Gene Name (Vector)
syntaxin 1B
Gene Symbol
STX1B
HGNC ID
HGNC:18539
ORF Size (aa)
867
RefSeq ID
NM_052874
RefSeq Synonyms
NM_052874, BC062298,
Species
human
UniGene ID
Hs.542230

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.