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human STAR shRNA silencing Adenovirus

Name 
Ad-h-STAR-shRNA
Cat No 
shADV-224513
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human STAR.

shADV-224513
Ad-h-STAR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human STAR (steroidogenic acute regulatory protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
STARD1
Description (Vector)
STAR plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
Gene ID
6770
Gene Name (Vector)
steroidogenic acute regulatory protein
Gene Symbol
STAR
HGNC ID
HGNC:11359
ORF Size (aa)
858
RefSeq ID
NM_000349
RefSeq Synonyms
NM_000349, BC010550,
Species
human
UniGene ID
Hs.521535

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.