human ST3GAL6 shRNA silencing Adenovirus

Name 
Ad-h-ST3GAL6-shRNA
Cat No 
shADV-224462
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ST3GAL6.

shADV-224462
Ad-h-ST3GAL6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ST3GAL6 (ST3 beta-galactoside alpha-2,3-sialyltransferase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SIAT10; ST3GALVI
Description (Vector)
ST3GAL6 is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene ID
10402
Gene Name (Vector)
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Gene Symbol
ST3GAL6
HGNC ID
HGNC:18080
ORF Size (aa)
996
RefSeq ID
NM_006100
RefSeq Synonyms
NM_006100, NM_001323368, NM_001323367, NM_001323366, NM_001323365, NM_001323364, NM_001323363, NM_001323362, NM_001323360, NM_001323359, NM_001323358, NM_001323353, NM_001323352, NM_001271148, NM_001271147, NM_001271146, NM_001271145, NM_001271142, BC023312,
Species
human
UniGene ID
Hs.148716

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.