human SPAG11B shRNA silencing Adenovirus

Name 
Ad-h-SPAG11B-shRNA
Cat No 
shADV-224062
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SPAG11B.

shADV-224062
Ad-h-SPAG11B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SPAG11B (sperm associated antigen 11B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11
Description (Vector)
SPAG11B encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined.
Gene ID
10407
Gene Name (Vector)
sperm associated antigen 11B
Gene Symbol
SPAG11B
HGNC ID
HGNC:14534
ORF Size (aa)
402
RefSeq ID
NM_058206
RefSeq Synonyms
NM_058207, NM_058206, NM_058203, NM_058202, NM_058201, NM_058200, NM_016512, BC160085,
Species
human
UniGene ID
Hs.2717

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.