human SORCS1 shRNA silencing Adenovirus

Name 
Ad-h-SORCS1-shRNA
Cat No 
shADV-223993
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SORCS1.

shADV-223993
Ad-h-SORCS1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SORCS1 (sortilin related VPS10 domain containing receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hSorCS
Description (Vector)
SORCS1 encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
114815
Gene Name (Vector)
sortilin related VPS10 domain containing receptor 1
Gene Symbol
SORCS1
HGNC ID
HGNC:16697
ORF Size (aa)
3507
ORF Size (bp)
3507 bp
RefSeq ID
NM_052918
RefSeq Synonyms
NM_052918, NM_001206572, NM_001206571, NM_001206570, NM_001206569, NM_001013031, BC131597,
Species
human
UniGene ID
Hs.591915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.