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human SNTG2 shRNA silencing Adenovirus

Name 
Ad-h-SNTG2-shRNA
Cat No 
shADV-223908
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SNTG2.

shADV-223908
Ad-h-SNTG2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SNTG2 (syntrophin gamma 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
G2SYN; SYN5
Description (Vector)
SNTG2 encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
Gene ID
54221
Gene Name (Vector)
syntrophin gamma 2
Gene Symbol
SNTG2
HGNC ID
HGNC:13741
ORF Size (aa)
1239
ORF Size (bp)
1239 bp
RefSeq ID
NM_018968
RefSeq Synonyms
NM_018968, BC125251,
Species
human
UniGene ID
Hs.657453

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.