human SLITRK5 shRNA silencing Adenovirus

Name 
Ad-h-SLITRK5-shRNA
Cat No 
shADV-223663
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SLITRK5.

shADV-223663
Ad-h-SLITRK5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SLITRK5 (SLIT and NTRK like family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bA364G4.2; leucine rich repeat containing 11; leucine-rich repeat-containing protein 11; LRRC11; SLIT and NTRK-like protein 5; slit and trk like gene 5
Description (eCommerce)
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]) [taken from NCBI Entrez Gene (Gene ID: 26050)].
Description (Vector)
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 (PubMed 14557068)).(supplied by OMIM, Mar 2008)
Gene ID
26050
Gene Name (eCommerce)
SLIT and NTRK like family member 5
Gene Name (Vector)
SLIT and NTRK like family member 5
Gene Symbol
SLITRK5
HGNC ID
HGNC:20295
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2877
ORF Size (bp)
2877 bp
Protein Name (eCommerce)
SLIT and NTRK-like protein 5
RefSeq ID
NM_015567
RefSeq Synonyms
NM_015567, BC103509, BC098287, BC098106,
Research Areas
Axonogenesis,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology,developmental_biology,neurobiology
Species
human
Target Sentence
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]) [taken from NCBI Entrez Gene (Gene ID: 26050)].
UniGene ID
Hs.591208
UniProt ID (eCommerce)
O94991

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.