human SLC39A14 shRNA silencing Adenovirus

Name 
Ad-h-SLC39A14-shRNA
Cat No 
shADV-223458
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SLC39A14.

shADV-223458
Ad-h-SLC39A14-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC39A14 (solute carrier family 39 member 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cig19; HCIN; HMNDYT2; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; zinc transporter ZIP14; ZIP14; ZIP-14; zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14
Description (eCommerce)
ZIP14 may mediate cellular uptake of nontransferrin-bound iron (By similarity). It is a broad-scope metal ion transporter with a preference for zinc uptake [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15043].
Description (Vector)
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 (PubMed 12659941)).(supplied by OMIM, Mar 2008)
Gene ID
23516
Gene Name (eCommerce)
solute carrier family 39 member 14
Gene Name (Vector)
solute carrier family 39 member 14
Gene Symbol
SLC39A14
HGNC ID
HGNC:20858
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
Protein Name (eCommerce)
Zinc transporter ZIP14
RefSeq ID
NM_015359
RefSeq Synonyms
NM_015359, NM_001135154, NM_001135153, NM_001128431, BC015770,
Research Areas
Golgi Apparatus,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
ZIP14 may mediate cellular uptake of nontransferrin-bound iron (By similarity). It is a broad-scope metal ion transporter with a preference for zinc uptake [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15043].
UniGene ID
Hs.491232
UniProt ID (eCommerce)
Q15043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.