human SLC10A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLC10A1.
shADV-223067
Ad-h-SLC10A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLC10A1 (solute carrier family 10 member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NTCP
Description (Vector)
SLC10A1 belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
Gene ID
6554
Gene Name (Vector)
solute carrier family 10 member 1
Gene Symbol
SLC10A1
HGNC ID
HGNC:10905
ORF Size (aa)
1050
RefSeq ID
NM_003049
RefSeq Synonyms
NM_003049, BC136355, BC126298, BC074724, BC069822, BC069799,
Species
human
UniGene ID
Hs.952
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.