human SIGMAR1 shRNA silencing Adenovirus

Name 
Ad-h-SIGMAR1-shRNA
Cat No 
shADV-222997
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SIGMAR1.

shADV-222997
Ad-h-SIGMAR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SIGMAR1 (sigma non-opioid intracellular receptor 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP
Description (Vector)
SIGMAR1 encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Gene ID
10280
Gene Name (Vector)
sigma non-opioid intracellular receptor 1
Gene Symbol
SIGMAR1
HGNC ID
HGNC:8157
ORF Size (aa)
672
RefSeq ID
NM_005866
RefSeq Synonyms
NM_147157, NM_005866, NM_001282209, NM_001282208, NM_001282207, NM_001282206, NM_001282205, BC004899,
Species
human
UniGene ID
Hs.522087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.